Reports from Guangzhou Medical University Advance Knowledge in Biomarkers (General Anesthesia Induces Acute Cell-free Dna Methylation Changes In Peripheral Blood).

A study conducted at Guangzhou Medical University in China explored the impact of general anesthesia on DNA methylation in surgical lung nodule patients. The research identified 4,562 differentially methylated regions induced by general anesthesia, which were associated with tissue damage and repair responses. These methylation changes were linked to postoperative coagulation functions and could potentially serve as predictive biomarkers for coagulation disorders after surgery. [Extracted from the article]