The SinRSlrR heteromer attenuates transcription of a long operon of flagellar genes in Bacillus subtilis.

The article discusses how Bacillus subtilis differentiates into motile and non-motile cells, impacting dispersal and biofilm formation. The activity of transcription factors SwrADegU and SinRSlrR influences the frequency of motile cells by regulating the fla/che flagellar operon. Through ChIP-Seq analysis, researchers identified binding sites of SinRSlrR within the operon, showing how these factors control transcriptional elongation and gene expression in bacteria. This study provides insights into the complex regulatory mechanisms governing cell motility and biofilm formation in Bacillus subtilis. [Extracted from the article]