The prevalence of multiple organ dysfunction syndrome and its relationship with clinical variables in intensive care unit patients in Iran, 2022.

Background: Hospitalization in intensive care units (ICUs) often leads to complications. One such complication is multi-organ dysfunction syndrome (MODS). This study aimed to determine the prevalence of MODS and its relationship with clinical variables in ICU patients in Iran, 2022. Methods: This cross-sectional, descriptive-analytical study included 194 ICU patients from Kermanshah hospitals, selected between 30 April and 1 September 2022. Data collection tools included patient demographic forms, Marshall et al.'s MODS calculation formula (1995), shock index, mNUTRIC, SOFA, APACHE II, and free water deficit. Data were analyzed using the SPSS-25 software. Results: The study found that 32% were aged 41–60, and 69.6% were male. The average MODS score was 6.87 ± 1.59 (ranging from 0 to 24), with a prevalence of 56.2%. MODS was significantly related to clinical variables such as the number of days in the hospital, days in ICU, number of involved organs, Glasgow Coma Scale (GCS), partial pressure of oxygen (PaO₂), shock index, APACHE II score, SOFA score, mNUTRIC score, and free water deficit (P < 0.05). Conclusion: MODS is highly prevalent among ICU patients. Key clinical factors associated with MODS include the duration of hospitalization, ICU stay, mechanical ventilation, number of involved organs, GCS, PaO₂, shock index, APACHE II, SOFA, mNUTRIC, and free water deficit. Attention to these factors in clinical planning and management could be beneficial in addressing MODS in ICU patients. [ABSTRACT FROM AUTHOR]