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Patent Issued for Artificial genome manipulation for gene expression regulation (USPTO 12163149).

Source :
Blood Weekly; 1/2/2025, p703-703, 1p
Publication Year :
2025

Abstract

The patent "Artificial genome manipulation for gene expression regulation" by inventors from South Korea focuses on controlling gene expression to treat diseases caused by gene duplication. The patent involves an expression control composition with a guide nucleic acid targeting the transcriptional regulatory region of a duplicate gene. Specifically, the patent addresses treating Pelizaeus-Merzbacher disease (PMD) using Campylobacter jejuni-derived Cas9 protein and guide RNAs. This patent highlights the importance of understanding gene expression mechanisms for disease treatment and improvement. [Extracted from the article]

Details

Language :
English
ISSN :
10656073
Database :
Complementary Index
Journal :
Blood Weekly
Publication Type :
Periodical
Accession number :
181854848