Genetic Blueprints in Lung Cancer: Foundations for Targeted Therapies.

Simple Summary: This article explores the molecular pathways involved in lung cancer, alongside genomic alterations and genetic syndromes associated with the disease. It also reviews testing methods and their role in advancing personalized treatment approaches, offering insights into current therapeutic strategies. This article provides a comprehensive overview of lung cancer from a genetic perspective, emphasizing the molecular pathways involved in its pathogenesis. This review presents the genetic syndromes and key genomic variations, including alterations and instabilities, contributing to tumor development and progression. Furthermore, advancements in genomic testing, such as liquid biopsy, are explored, highlighting their utility in early diagnosis, prognostic evaluation, and personalized treatment strategies. The role of biomarkers in informing therapeutic decisions and optimizing patient outcomes is also examined, offering insights into their potential to refine clinical interventions. This review aims to enrich the understanding of the genetic landscape of lung cancer, providing insights that may lead to improved diagnostic and therapeutic approaches. [ABSTRACT FROM AUTHOR]