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Advanced AI techniques for classifying Alzheimer's disease and mild cognitive impairment.
- Source :
- Frontiers in Aging Neuroscience; 2024, p1-9, 9p
- Publication Year :
- 2024
-
Abstract
- Background: Alzheimer's disease and mild cognitive impairment are often difficult to differentiate due to their progressive nature and overlapping symptoms. The lack of reliable biomarkers further complicates early diagnosis. As the global population ages, the incidence of cognitive disorders increases, making the need for accurate diagnosis critical. Timely and precise diagnosis is essential for the effective treatment and intervention of these conditions. However, existing diagnostic methods frequently lead to a significant rate of misdiagnosis. This issue underscores the necessity for improved diagnostic techniques to better identify cognitive disorders in the aging population. Methods: We used Graph Neural Networks, Multi-Layer Perceptrons, and Graph Attention Networks. GNNs map patient data into a graph structure, with nodes representing patients and edges shared clinical features, capturing key relationships. MLPs and GATs are used to analyse discrete data points for tasks such as classification and regression. Each model was evaluated on accuracy, precision, and recall. Results: The AI models provide an objective basis for comparing patient data with reference populations. This approach enhances the ability to accurately distinguish between AD and MCI, offering more precise risk stratification and aiding in the development of personalized treatment strategies. Conclusion: The incorporation of AI methodologies such as GNNs and MLPs into clinical settings holds promise for enhancing the diagnosis and management of Alzheimer's disease and mild cognitive impairment. By deploying these advanced computational techniques, clinicians could see a reduction in diagnostic errors, facilitating earlier, more precise interventions, and likely to lead to significantly improved outcomes for patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- ALZHEIMER'S disease diagnosis
COGNITION disorders diagnosis
ALZHEIMER'S disease
ARTIFICIAL intelligence
RESEARCH evaluation
CONVOLUTIONAL neural networks
HAMILTON Depression Inventory
COGNITION disorders
COMPUTER-aided diagnosis
ARTIFICIAL neural networks
STATISTICAL reliability
DEEP learning
NEUROPSYCHOLOGICAL tests
ACCURACY
MACHINE learning
DATA analysis software
PSYCHOLOGICAL tests
REGRESSION analysis
Subjects
Details
- Language :
- English
- ISSN :
- 16634365
- Database :
- Complementary Index
- Journal :
- Frontiers in Aging Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 181641664
- Full Text :
- https://doi.org/10.3389/fnagi.2024.1488050