Research Results from Sichuan University Update Knowledge of Brain Metastasis (MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition).

Researchers at Sichuan University have developed a nanomedicine called dBET6@CFMPD that combines PROTAC with photodynamic therapy (PDT) to target breast cancer and brain metastases. This innovative therapy has shown promising results in inhibiting primary and metastatic tumors, offering potential in cancer combination therapy. The study highlights the importance of effective drug delivery systems in enhancing antitumor responses. For more information, the full research article can be accessed in Nature Communications. [Extracted from the article]