Research from Heidelberg University in the Area of Radiation Oncology Described (Mixed- and multi-relative biological effectiveness model simultaneous optimization in carbon ion radiotherapy: A proof-of-concept).

Research from Heidelberg University explores the use of different relative biological effectiveness (RBE) models in carbon ion radiotherapy (CIRT) to optimize treatment plans. The study introduces a framework that considers multiple RBE models simultaneously, allowing for mixed- or multi-RBE optimization in CIRT. By incorporating various RBE models, the research aims to address challenges in translating RBE predictions and provide tailored patient treatment plans. The study successfully applied these optimization strategies to clinical cases, demonstrating the potential benefits of using mixed- and multi-RBE approaches in CIRT. [Extracted from the article]