National Veterinary Assay Laboratory Reports Findings in Classical Swine Fever Virus [Efficacy of GPE- strain live attenuated vaccine and CP7_E2alf strain recombinant live vaccine (marker vaccine) against Japanese epidemic classical swine fever...].

A recent study conducted in Tokyo, Japan, focused on the efficacy of two vaccines, the GPE strain live attenuated vaccine and the CP7_E2alf strain recombinant live vaccine, against the Japanese epidemic classical swine fever virus. The research aimed to assess the effectiveness of both vaccines in pigs through experimental challenge tests and evaluate the DIVA ability of the marker vaccine. Results indicated that both vaccines were effective against the Japanese epidemic strain, but the ELISA antibody detection kits had limited ability to discriminate the marker vaccine. The study concluded that alternative detection methods and enhancement of ELISA kits are needed to achieve CSF-free certification using vaccines with DIVA functionality. [Extracted from the article]