OPN5 and TRPV4 subserve intrinsic photosensitivity in mouse corneal epithelium.

The article discusses the role of OPN5 and TRPV4 in the intrinsic photosensitivity of mouse corneal epithelium, which helps protect the eye from harmful radiation. The study found that exposure to UVB photons can lead to inflammation, pain, vision loss, and potentially cancer. The research suggests that corneal epithelial cells are intrinsically photosensitive and utilize a phototransduction pathway to release cytokines and alert the visual system of harmful irradiation. [Extracted from the article]