Adsorption of amoxicillin by chitosan and alginate biopolymers composite beads.

Due to its widespread use and incomplete breakdown in the human body, amoxicillin has been detected in receiving water bodies. This raises significant concerns, like the promotion of antibiotic resistance, toxicity towards aquatic life, disruption of the natural balance of microbial communities within these water bodies, and the struggle of effectively removal by the traditional wastewater treatment plants. Consequently, exploring new processes to complement the existing methods is crucial. Adsorption, a promising highly efficient, selective, and versatile technique, can effectively remove contaminants, making it useful in various industries such as water treatment, pharmaceuticals, and environmental remediation. Several adsorbents are documented in the literature for drug adsorption; however, their fabrication often involves more complex steps and substances compared to chitosan and alginate, which are natural polymers that are biocompatible, non-toxic, and biodegradable. Their tunable properties and ease of modification enhance their efficacy in environmental remediation. Therefore, the novelty of this article is to understand the interaction of amoxicillin with chitosan and alginate adsorbents easily synthetized using the dripping technique. This approach allows us to explore basic principles that can be applied to more complex systems in future studies. The optimal pH for both beads was found to be 4, with adsorption capacities of 74.2 ± 0.3 mg g⁻¹ for alginate and 80.4 ± 0.2 mg g⁻¹ for chitosan, using 1 g of adsorbent. Kinetics studies indicated that external diffusion governs adsorption for alginate, while internal diffusion governs adsorption for chitosan. This approach underscores the potential of chitosan and alginate beads as effective adsorbents for mitigating antibiotic contamination in water systems, offering a sustainable complement to traditional treatment methods. [ABSTRACT FROM AUTHOR]