Editorial: Harnessing the potential of FLASH: questions we must address prior to effective clinical translation.

The editorial discusses the potential of FLASH radiotherapy, which delivers ultra-high dose rates, for cancer treatment with reduced side effects. While promising, questions remain regarding safe clinical translation for curative cancer care, as seen in studies on osteoradionecrosis in animals. The Research Topic includes articles addressing gaps in knowledge and technology for effective clinical translation of FLASH, focusing on dose rates, normal tissue sparing, tumour efficacy, and machine limitations. Despite remaining questions, this research contributes to the efficient clinical translation of FLASH. [Extracted from the article]