AN OVERVIEW OF JANUS KINASE INHIBITORS.

With a better understanding of the pathogenesis of inflammatory rheumatic diseases, different treatments pathways have emerged. In recent years, Janus kinase inhibitors (JAKinibs) have become one of these treatment pathways. It has come into clinical use as an effective treatment agent, especially in rheumatoid arthritis and spondyloarthropathy. In the 21^st-century, experimental and clinical studies are being conducted on JAKinibs in different disease groups apart from rheumatological diseases around the world. In this review, we aimed to briefly discuss the historical development and clinical use of JAKinibs. [ABSTRACT FROM AUTHOR]