New Study Findings from Rawalpindi Medical University Illuminate Research in Sensorineural Hearing Loss [Association of recurrent A1090E variant of OTOFERLIN (OTOF) gene with non-syndromic hereditary sensorineural hearing loss in Pakistani...].

A recent study conducted at Rawalpindi Medical University in Pakistan investigated the association of the otoferlin A1090E variant with severe to profound non-syndromic hereditary sensorineural hearing loss in Pakistani cochlear implant recipients. The research, which included 100 cases and 100 healthy individuals, found that the A1090E variant did not correlate with hearing loss risk in the study population. Despite the presence of the variant in both cases and controls, it did not show an association with disease risk, suggesting a potential protective role in hearing loss. The study's findings were published in the Khyber Medical University Journal. [Extracted from the article]