Shared genetic basis and causality between schizophrenia and inflammatory bowel disease: evidence from a comprehensive genetic analysis.

The article discusses research which examined the magnitude of shared genetic components and the causality relationship between schizophrenia (SCZ) and inflammatory bowel disease (IBD). Topics include the findings of genetic pleiotropic analysis aimed to uncover shared loci, genes, or biological processes between SCZ and each of IBD, ulcerative colitis (UC), and Crohn's disease (CD) and the biological mechanism and therapeutic targets underlying these two disorders.