Editorial: Novel approaches to targeting the vasculature and metabolome to prevent brain aging and related diseases.

The editorial discusses the importance of maintaining brain health through targeting the vasculature and metabolome to prevent brain aging and related diseases. It highlights the role of neurovascular coupling, the neurovascular unit, and the blood-brain barrier in ensuring brain homeostasis. Various studies presented in the editorial focus on different aspects of neurovascular health, such as the role of perivascular macrophages in ALS, neurotrophic factor receptor in diabetic macular edema, and pericytes in multiple sclerosis. The research emphasizes the significance of understanding and addressing disruptions in the neurovascular unit and metabolic processes to prevent cognitive decline and neurodegenerative diseases. [Extracted from the article]