More than half of chronic rhinosinusitis with nasal polyps (CRSwNP) patients treated with dupilumab experience early and fast olfactory improvement within 28 days.

The article discusses the impact of dupilumab treatment on olfactory function in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). The study found that more than half of patients experienced rapid improvement in olfactory function within 28 days of treatment, with significant enhancements in smell perception. Patients who were responsive to oral corticosteroids showed better results with dupilumab treatment. The findings suggest that dupilumab could be an effective and fast-acting option for improving olfactory function in CRSwNP patients, with potential implications for treatment stratification based on corticosteroid responsiveness. [Extracted from the article]