Theme 6 Tissue Biomarkers.

Authors :: Henne, C.
Brännström, T.
Zetterström, P.
Hayashi, S.
Yamasaki, R.
Kobayakawa, Y.
Kira, J.-i.
Isobe, N.
Bowser, R.
Gopalakrishnan, L.
Sethi, P.
Cappelli, S.
Bartolini, G.
Agbas, A.
Buratti, E.
Luthi-Carter, R.
Sharma, S.
Cortes-Perez, C.
Di Curzio, D.
Vandenakker, A.
Source :: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration; 2024 Suppl 1, Vol. 25, p185-196, 12p
Publication Year :: 2024
Abstract: The article discusses various studies and findings related to biomarkers and disease progression in amyotrophic lateral sclerosis (ALS). It highlights the importance of identifying biomarkers to improve clinical phenotyping and develop new therapeutic targets for ALS. The studies focus on different biomarkers such as tissue biomarkers, calcium-binding proteins, TAR DNA-binding protein 43 (TDP-43), endogenous retrovirus-K (ERVK), and adaptive immune response markers. The research aims to provide insights into the pathogenesis of ALS, identify potential diagnostic and prognostic biomarkers, and explore therapeutic strategies for ALS treatment. [Extracted from the article]