Three-component Domino Reaction in Aqueous Media for the Synthesis of New Indeno[1,2-b]pyrroles and Pyrrole-fused Isocoumarins and a Study of Their Antibacterial Properties.

The article discusses the synthesis of new indeno[1,2-b]pyrroles and pyrrole-fused isocoumarins in aqueous media using a three-component domino reaction. These compounds have shown various biological activities, including antimicrobial properties. The study explores the feasibility of preparing these compounds, which are structurally similar to known antimicrobial agents, and evaluates their antibacterial activity against different strains. The results show promising antimicrobial activities, suggesting the potential of these compounds as novel antimicrobial agents. [Extracted from the article]