EVALUATING THE EFFECTIVENESS OF PLATELET RICH FIBRIN IN PROMOTING SOFT TISSUE HEALING AFTER TOOTH EXTRACTION IN SMOKERS.

Platelet-rich fibrin (PRF) is a novel approach to tissue regeneration is emerging as a valuable tool to enhance healing in numerous dental and oral surgery procedures. The aim of present study is to evaluate the efficacy of Platelet Rich Fibrin on soft tissue healing in the experimental group in contrast to the control group and to compare the rate of soft tissue healing between the two groups and to assess the presence or absence of infection. 30 patients (15 patients each as case and control smokers) following tooth extraction. The patients were split into two groups, 15 patients in each Group A: Experimental group: Immediately after extraction, PRF was placed and wound secured with sutures. Group B: Control group: Immediately following extraction, the wound was secured with sutures. Follow up was done on day 3, day 7 and day 15. Both the groups showed statistically significant healing over time (days 3 through 15). Healing on days 3 and 7, between both the groups was not statistically significant and showed no difference. However, on day 15, the healing in the case group was much better. In conclusion, this study has shown the efficacy of PRF in wound healing following tooth extraction in smokers. We can safely conclude that PRF is a healing biomaterial which can be employed safely. [ABSTRACT FROM AUTHOR]