Acetyl-L-carnitine Improves Depressive-like Behaviors Through Nitric Oxide Modulation in the Cuprizone Intoxication Mouse Model of Multiple Sclerosis.

The article presents a study which evaluated the effects of acetyl-L-carnitine (ALC) in attenuating depressive-like symptoms in the cuprizone intoxication mouse model. Topics discussed include categories of C57BL/6 mice, RNA extraction, reverse transcription, and quantitative R-PCR, and effects of acetyl-L-carnitine on demyelination.