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Towards personalized vaccines.

Authors :
Montin, Davide
Santilli, Veronica
Beni, Alessandra
Costagliola, Giorgio
Martire, Baldassarre
Mastrototaro, Maria Felicia
Ottaviano, Giorgio
Rizzo, Caterina
Sgrulletti, Mayla
Del Giudice, Michele Miraglia
Moschese, Viviana
Source :
Frontiers in Immunology; 2024, p1-11, 11p
Publication Year :
2024

Abstract

The emergence of vaccinomics and system vaccinology represents a transformative shift in immunization strategies, advocating for personalized vaccines tailored to individual genetic and immunological profiles. Integrating insights from genomics, transcriptomics, proteomics, and immunology, personalized vaccines offer the promise of enhanced efficacy and safety, revolutionizing the field of vaccinology. However, the development of personalized vaccines presents multifaceted challenges, including technical, ethical, economic, and regulatory considerations. Addressing these challenges is essential to ensure equitable access and safety of personalized vaccination strategies. Despite these hurdles, the potential of personalized vaccines to optimize responses and mitigate disease burden underscores the significance of ongoing research and collaboration in advancing precision medicine in immunization. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16643224
Database :
Complementary Index
Journal :
Frontiers in Immunology
Publication Type :
Academic Journal
Accession number :
180669028
Full Text :
https://doi.org/10.3389/fimmu.2024.1436108