Findings from Southern Medical University in Alpha Thalassemia Reported [Quantification of Human Embryonic Z-globin Chains In Southeast Asian Deletion (--sea) Carriers].

A study conducted at Southern Medical University in Guangzhou, People's Republic of China, focused on quantifying zeta-globin in alpha-thalassemia carriers, aiming to understand its expression patterns. The research utilized various methods, including ELISA and LC-MS/MS, to quantify zeta-globin levels in a large cohort of individuals. The study concluded that the findings could contribute to future genotype-phenotype studies on the mechanisms of delayed hemoglobin switch in alpha-thalassemia. [Extracted from the article]