Double-stranded DNA reduces dsRNA degradation in the saliva and significantly enhanced RNAi-mediated gene silencing in Halyomorpha halys.

The article discusses the use of RNA interference (RNAi) as a targeted gene silencing approach for managing the invasive pest Halyomorpha halys in agriculture. The research found that double-stranded DNA (dsDNA) can protect dsRNA from degradation in the insect's saliva, enhancing gene silencing efficiency. While the dsDNA-based formulation improved gene silencing when fed with dsRNA, further investigation is needed to understand factors affecting dsRNA delivery in H. halys. This study suggests potential for developing cost-effective formulations to enhance RNAi efficacy in pest control. [Extracted from the article]