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Mixed‐Genotype HCV Direct Acting Antiviral Outcomes: A CANUHC Analysis.

Authors :
Imsirovic, Haris
Macphail, Gisela
Conway, Brian
Fraser, Chris
Borgia, Sergio
Smyth, Daniel
Wong, Alexander
Vachon, Marie‐Louise
Webster, Duncan
Liu, Hongqun
Feld, Jordan
Lee, Sam
Cooper, Curtis
Source :
Journal of Viral Hepatitis; Nov2024, Vol. 31 Issue 11, p775-779, 5p
Publication Year :
2024

Abstract

The prevalence of mixed hepatitis C virus (HCV) genotype infection in a representative Canadian HCV cohort is reported and virological response with direct acting antiviral (DAA) treatment was evaluated. 3272 HCV‐positive participants were enrolled, of which 2945 (90.0%) initiated DAA therapy. 0.8% were identified with mixed genotype infection. Overall sustained virological response (SVR) was 99.1% and did not differ based on mixed genotype status. Any historical disadvantage to achieving cure with HCV treatment in mixed genotype infection has been overcome by current DAA regimens. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13520504
Volume :
31
Issue :
11
Database :
Complementary Index
Journal :
Journal of Viral Hepatitis
Publication Type :
Academic Journal
Accession number :
180411010
Full Text :
https://doi.org/10.1111/jvh.13995