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Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus.

Authors :
Vu Ngoc Toan
Do Son Hai
Hoang Thi Kim Van
Nguyen Minh Tri
Duong Ngoc Toan
Nguyen Thi Thanh Maia
Nguyen Dinh Thanh
Source :
RSC Medicinal Chemistry; Oct2024, Vol. 15 Issue 10, p3395-3417, 23p
Publication Year :
2024

Details

Language :
English
ISSN :
26328682
Volume :
15
Issue :
10
Database :
Complementary Index
Journal :
RSC Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
180355288
Full Text :
https://doi.org/10.1039/d4md00334a