Reports Outline Endoscopy Study Results from University of Pennsylvania (Mechanistic Insights From Sleep Endoscopy Related To Oronasal Mask Failures: a Case Report).

A recent study conducted at the University of Pennsylvania focused on a 71-year-old male with severe obstructive sleep apnea and nasal septal deviation who experienced persistent obstructive events while using positive airway pressure (PAP) therapy delivered via an oronasal mask. The study utilized drug-induced sleep endoscopy with PAP titration to determine the mechanism of oronasal mask failure, revealing tongue base collapse as the cause. Following nasal surgery, the patient was able to tolerate nasal continuous PAP at a low therapeutic pressure, resulting in improvement in his obstructive sleep apnea. The research highlights the effectiveness of drug-induced sleep endoscopy with PAP in identifying the mechanistic cause of oronasal mask failure. [Extracted from the article]