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A NH2-Cu-MOF for promising antibacterial application.

Authors :
Li, Zhenxi
Cheng, Jing
Xie, Zhixin
Chen, Linlin
Source :
Scientific Reports; 10/10/2024, Vol. 14 Issue 1, p1-6, 6p
Publication Year :
2024

Abstract

A copper-based metal-organic framework named NH<subscript>2</subscript>-Cu-MOF has been synthesized and utilized as an effective broad-spectrum antimicrobial material in this article. The obtained NH<subscript>2</subscript>-Cu-MOF exhibits satisfying antibacterial activity against both gram-positive bacteria (S. aureus and S. epidermidis) and gram-negative bacteria (E. coli and K. peneumoniae). Additionally, the biocompatibility of this NH<subscript>2</subscript>-Cu-MOF has been validated through animal studies, showing no significant adverse effects, thereby confirming its high biocompatibility. These findings prove that NH<subscript>2</subscript>-Cu-MOF has positive effects upon the treatment of bacteria-infected wounds, which holds great potential to be applied in biochemistry field. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20452322
Volume :
14
Issue :
1
Database :
Complementary Index
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
180214714
Full Text :
https://doi.org/10.1038/s41598-024-74264-0