Influence of ion-releasing filler-containing gel application on dentin remineralization by using ultrasonic velocity measurement.

Purpose: The main objective of this study was to investigate the efficacy of S-PRG filler-containing gel application in promoting dentin remineralization using ultrasonic velocimetry. Methods: Root dentin slabs of bovine teeth were sliced and formed into rectangles, treated with 0.1 M lactate buffer (pH 4.75) for 10 min, and then immersed in artificial saliva (pH 7.0). This treatment was repeated three times a day for 28 days. S-PRG filler-containing gel (PRG) and high-fluorine concentration silver diamine fluoride (SDF) solution were used. The treatment methods were: 1) untreated group, 2) PRG one-off application group, 3) SDF oneoff application group, 4) PRG frequent-time application group, and 5) SDF frequent-time application group. After treatment, dentin slabs were soaked in 0.1 M lactate buffer solution and dipped in artificial saliva. This treatment was repeated 3 times a day for 28 days. Results: The ultrasonic velocity of the untreated samples decreased slightly during the experimental period. In the one-off application group, ultrasonic velocities of SDF and PRG increased rapidly on day 7 and then decreased slightly during the experimental period. In the frequent-time application group, ultrasonic velocities of SDF and PRG increased during the experimental period; specimens treated with SDF had significantly higher ultrasonic velocities on each measurement day compared to specimens treated with PRG. Conclusion: From the results of this experiment, it was concluded that the S-PRG filler-containing gel and silver diamine fluoride solution appear to promote remineralization and inhibit dentin demineralization. [ABSTRACT FROM AUTHOR]