Researchers from Emmanuel College Report on Findings in Cancer (Mutations, Substitutions, and Selection: Linking Mutagenic Processes To Cancer Using Evolutionary Theory).

A recent report from researchers at Emmanuel College in Boston, Massachusetts explores the link between mutagenic processes and cancer using evolutionary theory. The study emphasizes that cancers are the result of evolutionary events, where molecular variation accumulates in tissues and tumors. The researchers highlight the importance of sequencing this molecular variation to understand the mechanisms behind mutagenesis and identify cancer drivers. The report reviews tools to determine molecular signatures and cancer drivers, and discusses potential avenues for linking these metrics. The research has been peer-reviewed and published in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. [Extracted from the article]