Findings from University of Guilan Provides New Data about Antihyperlipidemic Agents (Investigation of the Behavior of A-casein Upon Binding To Fluvastatin and Pitavastatin: a Spectroscopic Study and Molecular Modeling).

A recent study conducted by researchers at the University of Guilan in Rasht, Iran, explored the interaction between alpha casein (alpha-CN) and two antihyperlipidemic drugs, fluvastatin (FLU) and pitavastatin (PIT). The study utilized fluorescence, UV absorption, and FTIR techniques, as well as molecular modeling, to investigate the binding of these drugs to alpha-CN. The results indicated that both FLU and PIT bind to alpha-CN, with PIT exhibiting a higher binding affinity. The study suggests that alpha-CN may act as a carrier for FLU and PIT drugs. This research has been peer-reviewed and published in the Journal of Structural Chemistry. [Extracted from the article]