New Acne Vulgaris Study Findings Recently Were Reported by Researchers at Queen Mary University of London (Loss-of-function Flg Mutations Are Associated With Reduced History of Acne Vulgaris In a Cohort of Patients With Atopic Eczema of...).

A recent study conducted by researchers at Queen Mary University of London explored the association between acne vulgaris (AV) and loss-of-function (LoF) filaggrin (FLG) gene mutations in a cohort of patients with atopic eczema (AE) of Bangladeshi ancestry in East London. The study found a significant reduction in the history of AV in patients with AE who had FLG LoF mutations compared to those without FLG mutations. Additionally, patients with severe AE were less likely to have a history of AV if they had an existing FLG LoF mutation. The research suggests that FLG LoF mutations may protect patients from developing AV in the context of AE. [Extracted from the article]