Data on Primary Ciliary Dyskinesia Described by Researchers at Pisa University Hospital (Impact of Tas2r38 Polymorphisms On Nasal Nitric Oxide and pseudomonas Infections In Primary Ciliary Dyskinesia: Relation To Genotype).

Researchers at Pisa University Hospital in Italy have conducted a study on primary ciliary dyskinesia (PCD), a respiratory condition. The study focused on the impact of TAS2R38 haplotypes, which encode the bitter taste receptor, on nasal nitric oxide (nNO) levels and Pseudomonas aeruginosa (P.a.) infections in PCD patients. The researchers found that the TAS2R38 haplotypes can affect nNO levels and may play a role in susceptibility to respiratory infections. They also discovered that TAS2R38 polymorphisms could potentially be used to develop new management strategies to prevent chronic P.a. infections. [Extracted from the article]