University College London (UCL) Reports Findings in Acute Chest Syndrome (Respiratory management of acute chest syndrome in children with sickle cell disease).

A report from University College London (UCL) discusses the respiratory management of acute chest syndrome (ACS) in children with sickle cell disease (SCD). ACS is a leading cause of respiratory distress and hospitalization in children with SCD, and its causes include fat embolism, venous thromboembolism, alveolar hypoventilation, and respiratory infections. The clinical presentation of ACS includes fever, chest pain, dyspnea, cough, wheeze, and hypoxia. Prevention, early recognition, and aggressive multidisciplinary team management are crucial in managing ACS. The report provides an overview of the epidemiology, pathophysiology, treatment, and preventative strategies for ACS in children with SCD. [Extracted from the article]