Patent Application Titled "Compositions And Methods For Screening Solid Tumors" Published Online (USPTO 20240294989).

The USPTO has published a patent application titled "Compositions And Methods For Screening Solid Tumors" by Quest Diagnostics Investments LLC. The application, filed by James Prentice, Kevin Qu, Heather Sanders, and Frederic Waldman, describes methods and compositions for detecting mutations in cancer-related genes in tumor samples. These methods aim to improve the detection of genetic alterations in heterogeneous tumors, helping predict patient responsiveness to specific therapies. The application specifically focuses on predicting lack of responsiveness to anti-HER-2 therapy in breast cancer patients by identifying specific mutations. The patent application provides detailed information on the techniques and primers used in the method. [Extracted from the article]