Gut Microorganism‐Mediated Neutralization of Mycotoxins: A Promising Approach to Combat Fungal Toxicity.

Mycotoxins, derived from fungi, pose significant threats to both human health and livestock well‐being. Their contamination of food and feed supplies results in substantial economic losses annually. Various chemical and physical methodologies are employed to mitigate the toxicity associated with these toxins. However, the utilization of microorganism‐mediated biotransformation presents a particularly promising and actively researched avenue for addressing the challenges posed by mycotoxins and enhancing food safety protocols. The intestinal microbiota engages in a dynamic interplay with mycotoxins, wherein mycotoxins disrupt the microbial equilibrium within the intestines and elevate epithelial barrier permeability, thereby impacting the intestinal ecosystem. Conversely, beneficial gut microbes possess the capacity to enzymatically degrade or sequester mycotoxins, thereby converting them into metabolites of reduced or negligible toxicity. This review encapsulates significant advancements in the biological detoxification of mycotoxins as evidenced by prior research endeavors. The discussion encompasses the repercussions of mycotoxin exposure on both human and animal health, alongside an examination of gut microbial‐based strategies for mycotoxin detoxification. [ABSTRACT FROM AUTHOR]