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Effect of Silicon Nitride Coating on Titanium Surface: Biocompatibility and Antibacterial Properties.

Authors :
Tani, Akina
Tsubouchi, Harumitsu
Ma, Lin
Taniguchi, Yurie
Kobayashi, Yasuyuki
Nakai, Mariko
Komasa, Satoshi
Hashimoto, Yoshiya
Source :
International Journal of Molecular Sciences; Sep2024, Vol. 25 Issue 17, p9148, 13p
Publication Year :
2024

Abstract

In recent years, with the advent of a super-aged society, lifelong dental care has gained increasing emphasis, and implant therapy for patients with an edentulous jaw has become a significant option. However, for implant therapy to be suitable for elderly patients with reduced regenerative and immunological capabilities, higher osteoconductive and antimicrobial properties are required on the implant surfaces. Silicon nitride, a non-oxide ceramic known for its excellent mechanical properties and biocompatibility, has demonstrated high potential for inducing hard tissue differentiation and exhibiting antibacterial properties. In this study, silicon nitride was deposited on pure titanium metal surfaces and evaluated for its biocompatibility and antibacterial properties. The findings indicate that silicon nitride improves the hydrophilicity of the material surface, enhancing the initial adhesion of rat bone marrow cells and promoting hard tissue differentiation. Additionally, the antibacterial properties were assessed using Staphylococcus aureus, revealing that the silicon nitride-coated surfaces exhibited significant antibacterial activity. Importantly, no cytotoxicity was observed, suggesting that silicon nitride-coated titanium could serve as a novel implant material. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16616596
Volume :
25
Issue :
17
Database :
Complementary Index
Journal :
International Journal of Molecular Sciences
Publication Type :
Academic Journal
Accession number :
179644225
Full Text :
https://doi.org/10.3390/ijms25179148