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Jasminanthoside – a new pregnane-steroid from Jasminanthes tuyetanhiae.
- Source :
- Natural Product Research; Sep2024, Vol. 38 Issue 18, p3112-3117, 6p
- Publication Year :
- 2024
-
Abstract
- A new pregnane steroid, jasminanthoside (1), together with three known compounds, telosmoside A7 (2), syringaresinol (3), and methyl 6–deoxy–3–O–methyl–β–D–allopyranosyl–(1→4)–β–D–oleandropyranoside (4) were isolated from the ethyl acetate extract of Jasminanthes tuyetanhiae roots collected in Vietnam. Their chemical structures were elucidated by NMR and MS spectroscopic data analysis along with the comparison of their data with the published ones in the literature. Although 4 was a known compound, its full NMR data were reported for the first time. All isolated compounds, evaluated for their α-glucosidase inhibition, showed activities stronger than the positive control acarbose. Among them, 1 was the best with the IC<subscript>50</subscript> value of 7.41 ± 0.59 µM. [ABSTRACT FROM AUTHOR]
- Subjects :
- ETHYL acetate
CHEMICAL structure
APOCYNACEAE
ACARBOSE
DATA analysis
PREGNANE
Subjects
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 38
- Issue :
- 18
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 179637676
- Full Text :
- https://doi.org/10.1080/14786419.2023.2216343