Princess Nourah Bint Abdulrahman University Researcher Releases New Study Findings on Receptor Protein-Tyrosine Kinases (Hesperidin Nanoformulation: A Potential Strategy for Reducing Doxorubicin-Induced Renal Damage via the...).

A recent study conducted at Princess Nourah Bint Abdulrahman University in Riyadh, Saudi Arabia, explored the potential of a nanoformulation of hesperidin, a compound known for its antioxidant and anti-inflammatory properties, in reducing kidney damage caused by doxorubicin. The researchers synthesized hesperidin nanoparticles and administered them to mice before inducing nephrotoxicity. The results showed that both hesperidin and hesperidin nanoparticles reduced the nephrotoxic effects of doxorubicin, with the nanoparticles showing the greatest reduction. The study suggests that hesperidin nanoparticles may have antioxidant, anti-inflammatory, and anti-apoptotic effects, making them a potential strategy for reducing doxorubicin-induced renal damage. [Extracted from the article]