Patent Application Titled "Central Nervous System Targeting Polynucleotides" Published Online (USPTO 20240285667).

A patent application titled "Central Nervous System Targeting Polynucleotides" has been published online by the US Patent and Trademark Office. The inventors of the application propose the use of adeno-associated virus (AAV) to deliver therapeutic agents to the central nervous system (CNS) for the treatment of CNS disorders. They discuss the need for better understanding and optimization of delivery parameters for viral particle distribution to achieve safer and more effective gene therapy. The application also describes the design, preparation, and formulation of AAV particles, as well as methods for their administration and delivery for the treatment of CNS diseases or disorders. [Extracted from the article]