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Effect of defocus incorporated multiple segments (DIMS) spectacle lenses on myopia progression in children: a retrospective analysis in a German real-life clinical setting.

Authors :
Neller, Birte
Neller, Kai
Schwahn, Hartmut
Mattern, Ann-Isabel
Devenijn, Machteld
Langenbucher, Achim
Seitz, Berthold
Kaymak, Hakan
Source :
BMC Ophthalmology; 9/12/2024, Vol. 24 Issue 1, p1-12, 12p
Publication Year :
2024

Abstract

Objectives: This retrospective analysis evaluates the treatment success of "Defocus Incorporated Multiple Segments" (DIMS) spectacle lenses in a real-life clinical setting in Germany. Materials and methods: Axial length (AL) and objective refraction of 166 eyes treated with DIMS at baseline and 12-month follow-up were analyzed. Annual AL growth rate within the range of physiological growth rate was considered a successful treatment. Myopia progression of ≥ -0.5 D/yr accounted as treatment success. Differences in percentages of treatment success of subgroups depending on baseline AL and age against treatment success of the total population were investigated. Results: Considering all eyes, treatment success regarding AL growth and myopia progression was achieved in 46% and 65%, respectively. Male eyes with moderate AL showed treatment success in a higher proportion (73%, p < 0.01; 89%, p < 0.01); eyes with high AL showed treatment success in a lower proportion (25%, p < 0.01; 51%, n.s.). Female eyes showed the same trend but without statistical significance (moderate AL: 49%; 68%; high AL: 40%; 62%). Younger children showed treatment success in a lower proportion (male: 11%, p < 0.01; 38%, p < 0.05; female: 25%, p < 0.01; 42%, p < 0.01). Older children showed treatment success in a higher proportion (male: 60%, p < 0.05; 78% p < 0.05; female: 53%, n.s.; 77% p < 0.05). Conclusions: Eyes with moderate baseline AL and of older children showed treatment success after 12 months of DIMS treatment. Eyes with a high baseline AL and of younger children showed treatment success in a smaller proportion, therefore combination treatment should be considered. In future studies, males and females should be assessed separately. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712415
Volume :
24
Issue :
1
Database :
Complementary Index
Journal :
BMC Ophthalmology
Publication Type :
Academic Journal
Accession number :
179604277
Full Text :
https://doi.org/10.1186/s12886-024-03666-5