Outcomes of combined ENT and oral surgical interventions in the management of obstructive sleep apnea.

Objective: To evaluate the outcomes of combined Ear, Nose, and Throat (ENT) and oral surgical interventions in managing moderate to severe Obstructive Sleep Apnea (OSA) in patients intolerant or unresponsive to Continuous Positive Airway Pressure (CPAP) therapy. Methods: This prospective cohort study involved 60 patients with moderate to severe OSA who underwent combined ENT and oral surgical procedures. Preoperative assessments included polysomnography and cephalometric analysis. Surgeries were tailored to individual anatomical abnormalities and included Uvulopalatopharyngoplasty (UPPP), Genioglossus Advancement (GA), Maxillomandibular Advancement (MMA), and nasal surgeries. Outcomes were measured by changes in the Apnea-Hypopnea Index (AHI), Epworth Sleepiness Scale (ESS), quality of life (QoL), and postoperative complications. Results: The mean AHI decreased from 38.2 to 16.5 events per hour (p < 0.001). ESS scores improved from 16.3 to 8.1 (p < 0.001), and QoL scores increased from 48.5 to 65.4 (p < 0.001). The surgical success rate was 75%, with a complication rate of 28.3%. Conclusion: Combined ENT and oral surgical interventions effectively reduce OSA severity and improve patient outcomes in those intolerant to CPAP, offering a viable alternative with an acceptable safety profile. [ABSTRACT FROM AUTHOR]