STUDY ON PERIOPERATIVE GLYCEMIC CONTROL AND POST-OPERATIVE INFECTIONS.

Diabetes mellitus (DM) represents a significant global health crisis, with its prevalence and complications posing substantial challenges, particularly in low- and middle-income countries like India. The relationship between chronic hyperglycemia, impaired immune response, and increased susceptibility to infections, especially surgical site infections (SSIs), is well-documented. SSIs, defined as infections occurring within 30 days post-surgery or up to one year if an implant is involved, can range from superficial to deep-seated organ infections, leading to prolonged hospital stays, increased morbidity and mortality, and substantial financial burdens on healthcare systems. This study investigates the impact of perioperative glycemic control on the incidence and severity of SSIs among Indian surgical patients. It aims to elucidate the relationship between preoperative and postoperative glycemic levels and the risk of SSIs, the correlation between the degree of hyperglycemia and SSI severity, and the predominant bacterial pathogens involved, including their antibiotic susceptibility profiles. Emerging evidence indicates that maintaining optimal glycemic control during the perioperative period is crucial for reducing the risk of SSIs. The study's findings are expected to fill the existing knowledge gap, providing valuable data to inform clinical guidelines and enhance the quality of care for surgical patients with diabetes in India. This research underscores the necessity for a multidisciplinary approach to glycemic management, involving surgeons, anesthesiologists, endocrinologists, and nursing staff, to achieve improved surgical outcomes and mitigate complications associated with hyperglycemia. [ABSTRACT FROM AUTHOR]