EP18.05: First trimester referral ultrasound following the introduction of the guidelines of the SIEOG: focus on false positives and false negatives.

This article analyzes the accuracy of first trimester referral ultrasounds compared to second trimester referral ultrasounds in detecting false positives and false negatives for structural anomalies in singleton pregnancies. The study found that the rate of false positive and false negative diagnoses in the first trimester ultrasounds was low. False negatives were mostly minor structural anomalies with little impact on management and counseling, or evolving anomalies that cannot be diagnosed in the first trimester. False positives were consistent with the natural history of the anomaly, although over-diagnosis was acknowledged as a limitation of first trimester referral ultrasounds. [Extracted from the article]