Eavesdropping on Ion Channels Using the Patch Clamp Technique: Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed.

The article provides an overview of the patch clamp technique, a method used to study ion channels in cells. It explains how the technique was developed and refined by researchers such as Kenneth Cole, Erwin Neher, and Bert Sakmann. The authors discuss the different patch configurations that have been developed and highlight the ongoing relevance of the technique in studying ion channels and its integration with other technologies. The patch clamp technique has greatly advanced our understanding of cellular electrophysiology and its role in diseases. [Extracted from the article]