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Bicentric lesion of colon cancer with postoperative fever: A case report.

Authors :
Wang, Mengyuan
Zao, Xiaobin
Ge, Zhiming
Fan, Xianxian
Jin, Li
Zhang, Jiucun
Zhao, Hongbo
Tie, Baoxia
Liang, Yijun
Song, Lianying
Liu, Jinglong
Wang, Yifei
Zhang, Shuxin
Yang, Yun
Source :
Oncology Letters; Oct2024, Vol. 28 Issue 4, pN.PAG-N.PAG, 1p
Publication Year :
2024

Abstract

Colon adenocarcinoma (COAD) is a malignant tumor type. Fever is the most common postoperative complication of COAD. The present study described the treatment of a patient with early-stage COAD with precancerous colon polyps and the possible cause of postoperative fever. The patient was a 48-year-old woman with intermittent hematochezia, defecation urgency and liquid feces. The patient received surgical treatment, a whole segment from the intestine was removed, which contained a 4-cm-long mass and a 2-cm-long firm mass. Within 3 days after the operation, the patient's incision healed well, but the body temperature increased to a range of 37.8–38.6°C. The suture was removed on the 10th postoperative day. After another three days, it was discovered that the upper end of the patient's surgical incision split to the anterior rectus abdominis sheath. The patient was provided with recombinant human acidic fibroblast growth factor to promote wound healing. The patient was finally diagnosed with rectosigmoid junction adenocarcinoma and precancerous colon polyps according to pathological examination results. The patient was given intravenous bevacizumab combined with irinotecan hydrochloride and oral capecitabine, and all drugs were repeatedly applied every 3 weeks, and a total of four treatment cycles were used. The cause of this postoperative fever was concluded to be anemia coming from chronic hematochezia and combined with deep wound dehiscence with secondary infection. The present study showcased that low-dose and short-course prophylactic adjuvant therapy is feasible for early-stage COAD with precancerous colon polyps. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17921074
Volume :
28
Issue :
4
Database :
Complementary Index
Journal :
Oncology Letters
Publication Type :
Academic Journal
Accession number :
179485636
Full Text :
https://doi.org/10.3892/ol.2024.14630