Research from Department of Immunology Has Provided New Data on Malaria (Expression patterns of immune checkpoint proteins and Plasmodium falciparum-induced cytokines in chronic hepatitis B virus-infected and uninfected individuals: A...).

A recent study conducted by the Department of Immunology explored the expression patterns of immune checkpoint proteins and Plasmodium falciparum-induced cytokines in individuals with chronic hepatitis B virus (CHB) infection. The study found that CHB individuals who do not require antiviral therapy at the present time have comparable levels of CD4+ and CD8+ T cells to HBV-negative individuals. Additionally, the ability to produce cytokines in response to malaria antigen stimulation was not significantly different between the two groups. These findings suggest that CHB individuals can be excluded from antiviral therapy at this stage of infection, but regular monitoring is still necessary to determine the need for future treatment. [Extracted from the article]