New Colon Cancer Study Results from Yonsei University College of Medicine Described (Inhibition of IRP2-dependent reprogramming of iron metabolism suppresses tumor growth in colorectal cancer).

A recent study conducted by Yonsei University College of Medicine has found that dysregulation of iron metabolism is linked to the development and progression of colorectal cancer (CRC). The study focused on the role of iron regulatory protein 2 (IRP2) in promoting tumor growth in CRC. The researchers discovered that inhibiting IRP2 resulted in a significant delay in tumor growth and developed IRP2 inhibitors that reduced IRP2 expression and hindered its interaction with iron-responsive elements. These findings suggest that targeting IRP2 could be a potential therapeutic strategy for CRC treatment. [Extracted from the article]