Study Results from University of Montreal Provide New Insights into Pharmacology [Endocannabinoid regulation of inward rectifier potassium (Kir) channels].

A recent study conducted by researchers at the University of Montreal has provided new insights into the pharmacology of endocannabinoids. The study focused on the inward rectifier potassium channel Kir2.1 and its role in regulating resting membrane potential in various cells. The researchers found that a subset of endocannabinoids can alter the conductance of Kir2.1 channels independently of cannabinoid receptors. These findings have potential implications for the function of cardiac, neuronal, and immune cells. The study was funded by several organizations, including the Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council of Canada. [Extracted from the article]