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ESASO classification relevance in the diagnosis and evolution in diabetic macular edema patients after dexamethasone implant treatment.

ESASO classification relevance in the diagnosis and evolution in diabetic macular edema patients after dexamethasone implant treatment.

Authors :
Moreno-Martínez, Almudena
Blanco-Marchite, Cristina
Andres-Pretel, Fernando
López-Martínez, Francisco
Donate-Tercero, Antonio
González-Aquino, Eva
Cava-Valenciano, Carlos
Panozzo, Giacomo
Copete, Sergio
Source :
Graefe's Archive of Clinical & Experimental Ophthalmology; Sep2024, Vol. 262 Issue 9, p2813-2821, 9p
Publication Year :
2024

Abstract

Purpose: To assess the clinical relevance of The European School for Advanced Studies in Ophthalmology (ESASO) classification in patients with diabetic macular edema (DME) after their first dexamethasone implant (DEXI) treatment. Methods: Retrospective real-world study conducted on consecutive DME patients who underwent DEXI treatment and were controlled at month-2. Subjects were initially classified according to the ESASO classification stages. The outcomes were anatomical biomarkers with spectral-domain optical coherence tomography (SD-OCT) and best-corrected visual acuity (BCVA). Results: A total of 128 patients were classified according to ESASO classification stages as early (7; 5.5%), advanced (100; 78.1%), and severe (21; 16.4%). At baseline, there were significant differences between stages in BCVA, central macular thickness (CMT), and tomography anatomical biomarkers (p < 0.05). Initial BCVA (logMAR) was 0.33 ± 0.10, 0.58 ± 0.34, and 0.71 ± 0.35 in the early, advanced, and severe stages, respectively (p < 0.05). At month-2, BCVA was 0.17 ± 0.15, 0.46 ± 0.29, and 0.69 ± 0.27 in those classified as early, advanced, and severe stages, respectively. At month-2, DME was resolved or improved in 6 (85.7%), 60 (60%), and 12 (60%) patients classified as early, advanced, and severe stages, respectively. Conclusions: There was a good correlation between BCVA and ESASO classification stages. Patients in the severe stage did not achieve visual acuity improvement over the study period. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0721832X
Volume :
262
Issue :
9
Database :
Complementary Index
Journal :
Graefe's Archive of Clinical & Experimental Ophthalmology
Publication Type :
Academic Journal
Accession number :
179460509
Full Text :
https://doi.org/10.1007/s00417-024-06473-2